Diagnostic and prognostic value of cardiac magnetic resonance imaging in assessing myocardial viability
Raymond Y Kwong, MD MPH, Hemanth Korlakunta, MD · Narrative review
BlueRipple Assessment
Before sending a patient with a damaged heart to revascularization, one question decides everything: is the muscle salvageable, or scarred dead? This review makes the case for cardiac MRI as the test that answers it best.
The key tool is late gadolinium enhancement, which marks scar tissue directly — letting MRI distinguish infarcted from viable muscle, predict whether function will recover after blood flow is restored, and inform prognosis. The authors present it as more accurate and clinically relevant than competing modalities for this specific job.
The practical takeaway is direct: use late-gadolinium MRI to assess viability before revascularizing in coronary disease. The resistance comes from nuclear cardiology departments whose SPECT and PET workflows MRI would displace.
We rate the evidence moderate: a well-referenced review from a respected center, but a synthesis rather than new data. Its clinical significance is solid — viability assessment directly drives revascularization decisions, and late-gadolinium MRI has since become a standard tool for it.
The original source
Kwong RY, Korlakunta H. Diagnostic and prognostic value of cardiac magnetic resonance imaging in assessing myocardial viability. Top Magn Reson Imaging. 2008 Feb;19(1):15-24. doi: 10.1097/RMR.0B013e31817d550c.
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