Right heart catheterization in patients with advanced heart failure: when to perform? How to interpret?
Michelle M Kittleson, MD PhD, Paolo Prestinenzi, MD, Luciano Potena, MD PhD · Narrative review
BlueRipple Assessment
In advanced heart failure, the difference between the right and wrong treatment often comes down to numbers you can only get with a catheter. This review is a practical guide to when to obtain them and how to read them.
Right heart catheterization measures the pressures and flows inside the failing heart, and the authors walk through its role across the spectrum — diagnosis, tailoring therapy, and the pivotal decisions about mechanical support devices and transplant candidacy, where hemodynamics are often decisive. The emphasis is on interpretation as much as indication.
The practical takeaway is to use the catheterization for hemodynamic clarity in advanced cases rather than relying on estimates when the stakes are highest. The resistance comes from general cardiologists and systems that underuse invasive monitoring out of unfamiliarity or caution about risk.
We rate the evidence moderate: focused, expert guidance with no declared conflicts, but a review without new primary data. Its clinical significance is solid and concrete — these readings directly drive transplant and device decisions for the sickest heart-failure patients, even if the affected population is narrow.
The original source
Kittleson MM, Prestinenzi P, Potena L. Right heart catheterization in patients with advanced heart failure: when to perform? How to interpret? Heart Fail Clin. 2021 Oct;17(4):647-660. doi: 10.1016/j.hfc.2021.05.009.
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