BlueRipple Health

Guidelines

Curated, plain-language updates on guidelines — each summarized and linked to its original source.

8 items

In Memoriam: ACC Past President Robert L. Frye, MD, MACC

The ACC mourns the loss of Robert L. Frye, MD, MACC, a distinguished physician, investigator, educator and leader whose career helped shape modern cardiovascular medicine, as well as the College. Frye, who served as ACC President from 1991-1992, leaves behind a legacy of service to patients and the profession spanning more than seven decades.

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Articles and Stories
August 7, 2026

Follow-Up of CENTRAL, DIRECT-PLUS Suggests Visceral Fat Reduction Has Lasting Metabolic Health Benefits

A long-term follow-up of the CENTRAL and DIRECT-PLUS trials published in Circulation suggests that despite long-term weight regain, visceral fat reduction during lifestyle intervention is associated with sustained improvements in metabolic health.

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Articles and Stories
June 11, 2026

ACC CardiaCast: Risk Assessment and Treatment of Hypertriglyceridemia

This episode of CardiaCast will feature a discussion on risk assessment and the treatment of hypertriglyceridemia.

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Articles and Stories
August 7, 2026

GBD Study 2023: LDL-C Burden Increasing Globally

The global burden attributable to elevated LDL-C has grown substantially since 1990, driven largely by population growth and aging despite significant declines in age-standardized rates, according to findings from the Global Burden of Disease Study 2023 (GBD 2023) Cholesterol Collaborators published July 29 in JAMA.

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Articles and Stories
August 6, 2026

CLASP IID: Residual MR and Gradient at 1 Year Post M-TEER

Patients who underwent mitral transcatheter edge-to-edge repair (M-TEER) with an optimal result were more likely to have improved hemodynamics and less likely to experience major adverse events, all-cause mortality, heart failure (HF) hospitalization or reintervention at one year

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Articles and Stories
June 12, 2026

SOGALDI-PEF: Baseline Renin Levels Predict BP Treatment Effect

Patients with low plasma renin levels had a more pronounced blood pressure (BP) reduction with spironolactone/dapagliflozin vs. dapagliflozin alone, in addition to seeing a more favorable impact on cardiovascular structure and function, while aldosterone levels exhibited no predictive value in treatment response

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Articles and Stories
June 10, 2026

First-ever guideline on cardiovascular-kidney-metabolic syndrome issued

The first-ever clinical practice guideline on cardiovascular-kidney-metabolic (CKM) syndrome from the American Heart Association and the American College of Cardiology details staging to assess how a person’s kidneys, metabolism

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June 9, 2026

Gum disease may be linked to plaque buildup in arteries, higher risk of major CVD events

DALLAS, Dec. 16, 2025 — There is increasing evidence that gum disease is associated with increased risk of cardiovascular events, including heart attack, stroke, atrial fibrillation, heart failure and cardiometabolic health conditions. Effective

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December 16, 2025