Curated, plain-language updates on guidelines — each summarized and linked
to its original source.
5 items
Follow-Up of CENTRAL, DIRECT-PLUS Suggests Visceral Fat Reduction Has Lasting Metabolic Health Benefits
A long-term follow-up of the CENTRAL and DIRECT-PLUS trials published in Circulation suggests that despite long-term weight regain, visceral fat reduction during lifestyle intervention is associated with sustained improvements in metabolic health.
Gum disease may be linked to plaque buildup in arteries, higher risk of major CVD events
DALLAS, Dec. 16, 2025 — There is increasing evidence that gum disease is associated with increased risk of cardiovascular events, including heart attack, stroke, atrial fibrillation, heart failure and cardiometabolic health conditions. Effective...
CLASP IID: Residual MR and Gradient at 1 Year Post M-TEER
Patients who underwent mitral transcatheter edge-to-edge repair (M-TEER) with an optimal result were more likely to have improved hemodynamics and less likely to experience major adverse events, all-cause mortality, heart failure (HF) hospitalization or reintervention at one year...
SOGALDI-PEF: Baseline Renin Levels Predict BP Treatment Effect
Patients with low plasma renin levels had a more pronounced blood pressure (BP) reduction with spironolactone/dapagliflozin vs. dapagliflozin alone, in addition to seeing a more favorable impact on cardiovascular structure and function, while aldosterone levels exhibited no predictive value in treatment response...
First-ever guideline on cardiovascular-kidney-metabolic syndrome issued
Guideline Highlights:
The first-ever clinical practice guideline on cardiovascular-kidney-metabolic (CKM) syndrome from the American Heart Association and the American College of Cardiology details staging to assess how a person’s kidneys, metabolism...